Product details
Background:
TPM2 rabbit pAb
Ucallm_WP7874-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TPM2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 31kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TPM2 |
| Specificity | This antibody detects endogenous levels of TPM2 at Human, Mouse,Rat |
| Gene Name | TPM2 TMSB |
| Protein Name | Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2) |
| Other Name | |
| Species | Human |
| Gene ID | 7169 |
| Uniprot | P07951, |
| Species.1 | Mouse |
| Gene ID.1 | 22004 |
| Uniprot.1 | P58774, |
| Species.2 | Rat |
| Gene ID.2 | 500450 |
| Uniprot.2 | P58775 |
| Cellular Localization | Cytoplasm, cytoskeleton . Associates with F-actin stress fibers. . |
| Tissue Expression | Present in primary breast cancer tissue, absent from normal breast tissue. |
| Signaling_pathway | Organismal Systems >> Circulatory system >> Cardiac muscle contraction;Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes |
| Research Areas | |
| Function | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. |
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