Product details
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TRIOBP rabbit pAb
Ucallm_WP6625-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TRIOBP |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 260kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TRIOBP |
| Specificity | This antibody detects endogenous levels of TRIOBP at Human, Mouse |
| Gene Name | TRIOBP KIAA1662 TARA HRIHFB2122 |
| Protein Name | TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin) |
| Other Name | |
| Species | Human |
| Gene ID | 11078 |
| Uniprot | Q9H2D6, |
| Species.1 | Mouse |
| Gene ID.1 | 110253 |
| Uniprot.1 | Q99KW3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm, cytoskeleton . Localized to F-actin in a periodic pattern. .; [Isoform 1]: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Midbody . Centrosomal localization occurs upon phosphorylation by PLK1 at Thr-457 and lasts from prophase to anaphase. At telophase, relocalizes to midbody. . |
| Tissue Expression | Widely expressed. Highly expressed in heart and placenta. Isoform 3 is expressed in fetal brain, retina and cochlea but is not detectable in the other tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | May regulate actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin. The localized formation of TARA and TRIO complexes coordinates the amount of F-actin present in stress fibers. May also serve as a linker protein to recruit proteins required for F-actin formation and turnover. |
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