SKU: WP2143 Categories: ,

TSSC4 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2143-100
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Product details

Background:

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Specifications

Size50μL/100μL
TargetTSSC4
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)36kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityTSSC4 Polyclonal Antibody detects endogenous levels of protein.
Gene NameTSSC4
Protein NameProtein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein)
Other Name
SpeciesHuman
Gene ID10078
UniprotQ9Y5U2,
Species.1Mouse
Gene ID.1
Uniprot.1Q9JHE7,
Species.2Rat
Gene ID.2
Uniprot.2Q5XIB1
Cellular Localization
Tissue ExpressionExpressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues.
Signaling_pathway
Research Areas
Functionsimilarity:Belongs to the TSSC4 family.,tissue specificity:Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues.,
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