TSSC4 Polyclonal Antibody
Product details
Background:
This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Specifications
| Size | 50μL/100μL |
| Target | TSSC4 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TSSC4 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TSSC4 |
| Protein Name | Protein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) |
| Other Name | |
| Species | Human |
| Gene ID | 10078 |
| Uniprot | Q9Y5U2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9JHE7, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q5XIB1 |
| Cellular Localization | |
| Tissue Expression | Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the TSSC4 family.,tissue specificity:Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues., |
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