Name: Tubulin β Monoclonal Antibody
SKU: WM0548
Price: 268 USD
Availability: InStock

Tubulin β Monoclonal Antibody

Ucallm_WM0548-50

Price range: $268.00 through $328.00

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SKU: WM0548-50

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Product details

Background:
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010],

Specifications

Target	Tubulin β
Reactivity	Human, Mouse, Rat, Bovine
Applications	WB, IP
MW(Calculated)	50kD
MW(Observed)
Host Species	Mouse
Isotype
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:1000-1:2000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification	Affinity purification
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	100000000000
Immunogen	Purified recombinant human Tubulin β protein fragments expressed in E.coli.
Sequence
Specificity	Tubulin β Monoclonal Antibody detects endogenous levels of Tubulin β protein.
Gene Name	TUBB1
Protein Name	Tubulin beta-1 chain
Other Name	TUBB1; / Tubulin beta-1 chain
Species	Human
Gene ID-1	81027
Uniprot	P07437,
Species.1	Mouse
Gene ID-2	545486
Uniprot.1	A2AQ07
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010],
Cellular Localization	Cytoplasm, cytoskeleton .
Tissue Expression	Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins.
Signaling_pathway	Cellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Cellular community - eukaryotes >> Gap junction;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Research Areas	>>Phagosome; / >>Gap junction; / >>Alzheimer disease; / >>Parkinson disease; / >>Amyotrophic lateral sclerosis; / >>Huntington disease; / >>Prion disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Pathogenic Escherichia coli infection; / >>Salmonella infection
Function	Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
RRID

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Tubulin β Monoclonal Antibody

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Tubulin β Monoclonal Antibody

Product details

Specifications

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