TULP3 rabbit pAb
Ucallm_WP17135-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009],
Specifications
| Size | 50μL/100μL |
| Target | TULP3 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 49kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TULP3 AA range: 257-307 |
| Specificity | This antibody detects endogenous levels of TULP3 at Human/Mouse |
| Gene Name | TULP3 TUBL3 |
| Protein Name | TULP3 |
| Other Name | |
| Species | Human |
| Gene ID | 7289 |
| Uniprot | O75386, |
| Species.1 | Mouse |
| Gene ID.1 | 22158 |
| Uniprot.1 | O88413 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. Cell membrane. Cell projection, cilium . Cytoplasm . Secreted . Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. . |
| Tissue Expression | Expressed at high levels in testis, ovaries, thyroid, and spinal chord. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the TUB family.,tissue specificity:Expressed at high levels in testis, ovaries, thyroid, and spinal chord., |
Please login to post questions
Related products
