TUSC1 rabbit pAb
Ucallm_WP17152-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | TUSC1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 23kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TUSC1 AA range: 120-170 |
| Specificity | This antibody detects endogenous levels of TUSC1 at Human/Mouse |
| Gene Name | TUSC1 |
| Protein Name | TUSC1 |
| Other Name | |
| Species | Human |
| Gene ID | 286319 |
| Uniprot | Q2TAM9, |
| Species.1 | Mouse |
| Gene ID.1 | 69136 |
| Uniprot.1 | Q673H1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | Widely expressed at low level. Expressed at higher level in testis, weakly expressed in muscle, colon, lung and spleen. Not detected in 3 non small cell lung carcinoma (NSCLC) cell lines with homozygous deletion of the 9p region, while it is down-regulated in 3 other tumor cell lines. |
| Signaling_pathway | |
| Research Areas | |
| Function | tissue specificity:Widely expressed at low level. Expressed at higher level in testis, weakly expressed in muscle, colon, lung and spleen. Not detected in 3 non small cell lung carcinoma (NSCLC) cell lines with homozygous deletion of the 9p region, while it is down-regulated in 3 other tumor cell lines., |
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