Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TXD11 AA range: 110-160
Specificity
This antibody detects endogenous levels of TXD11 at Human/Mouse
Gene Name
TXNDC11 EFP1
Protein Name
TXD11
Other Name
Species
Human
Gene ID
51061
Uniprot
Q6PKC3,
Species.1
Mouse
Gene ID.1
106200
Uniprot.1
Q8K2W3
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Endoplasmic reticulum membrane; Single-pass membrane protein .
Tissue Expression
Widely expressed at low level. Expressed at higher level in thyroid and prostate.
Signaling_pathway
Research Areas
Function
Function:May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.,sequence Caution:Intron retention.,similarity:Belongs to the protein disulfide isomerase family.,similarity:Contains 2 thioredoxin domains.,subunit:Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA.,tissue specificity:Widely expressed at low level. Expressed at higher level in thyroid and prostate.,