TXND8 rabbit pAb
Ucallm_WP16818-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TXND8 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 14kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TXND8 AA range: 64-114 |
| Specificity | This antibody detects endogenous levels of TXND8 at Human/Mouse/Rat |
| Gene Name | TXNDC8 SPTRX3 TRX6 |
| Protein Name | TXND8 |
| Other Name | |
| Species | Human |
| Gene ID | 255220 |
| Uniprot | Q6A555, |
| Species.1 | Mouse |
| Gene ID.1 | 67402 |
| Uniprot.1 | Q69AB2, |
| Species.2 | Rat |
| Gene ID.2 | 362525 |
| Uniprot.2 | Q69AB1 |
| Cellular Localization | Cytoplasm . Golgi apparatus . |
| Tissue Expression | Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.,miscellaneous:Increased levels, possibly caused by overexpression, are observed in morphologically abnormal spermatozoa from infertile men, suggesting that it may be used as a marker of aberrant spermatogenesis.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level)., |
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