Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TYW1B
Specificity
This antibody detects endogenous levels of TYW1B at Human
Gene Name
TYW1B RSAFD2
Protein Name
tRNA wybutosine-synthesizing protein 1 homolog B (Radical S-adenosyl methionine and flavodoxin domain-containing protein 2)
Other Name
Species
Human
Gene ID
441250
Uniprot
Q6NUM6
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity).