U-Blot® Boris / CTCFL Polyclonal Antibody
Product details
Background:BRD3 (Bromodomain Containing 3) is a member of the mammalian BET (Bromodomain Extra Terminal) family of proteins, binds hyperacetylated chromatin and has been reported to interact with acetylated Histone H4K5, Histone H4K12 and Histone H3K14. It plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Regulates transcription of the CCND1 gene.
Specifications
| Target | -- |
| Reactivity | Human |
| Applications | ChIP; ChIP-Seq; WB |
| MW(Calculated) | 96 kDa |
| Host Species | Rabbit |
| Isotype | IgG |
| Recommended Dilution Ratio | Applications Validated by Active Motif: ChIP: 5 µl per ChIP ChIP-Seq: 5 µl each WB: 1:500 - 1:2,000 dilution ChIP-Seq validation was performed by Active Motif's Epigenetics Services; the complete data set is available in the UCSC Genome Browser by clicking here . For CTCF , we also offer AbFlex ® CTCF Recombinant Antibody (rAb). For details, see Catalog No. 91285 . |
| Formulation | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| Purification | Affinity Purified |
| Storage | Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage. |
| Concentration | -- |
| Clonality | Polyclonal |
| Clone Number | -- |
| Immunogen | This antibody was raised against a peptide within the N-terminal region of human BORIS. |
| Specificity | -- |
| Gene Name | -- |
| Other Name | CT27, BORIS, CTCF-T, HMGB1L1 |
| Gene ID | -- |
| Cellular Localization | -- |
| Function | -- |
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