- Please choose product options by visiting U-Blot® Mouse TCR αβ/alpha-beta TCR Antibody (Desire-1).
- Please choose product options by visiting U-Blot® HPV16 L1/Major capsid protein L1 Antibody (H263.A2).
U-Blot® CD127 Mouse mAb
Ucallm_WM1840-50
Price range: $268.00 through $328.00
Product details
Background：
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015],
Specifications
| Size | 50μL/100μL |
| Target | IL-7R |
| Reactivity | Human |
| Applications | FC,IF |
| MW(Calculated) | 52kD |
| MW(Observed) | 70kD |
| Host Species | Mouse |
| Isotype | Mouse IgG1/Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:4000-1:20000;IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application |
| Formulation | PBS, pH 7.4 |
| Purification | Protein A |
| Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMMF0044 |
| Immunogen | |
| Specificity | Endogenous |
| Gene Name | IL7R |
| Protein Name | Interleukin-7 receptor subunit alpha |
| Other Name | IL7R;Interleukin-7 receptor subunit alpha;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CDw127;CD antigen CD127 |
| Species | Human |
| Gene ID | 3575 |
| Uniprot | P16871 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 4]: Secreted. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
Please login to post questions
Related products
