Product details
Background：
U-Blot® CD223 (LAG-3) Mouse mAb
Ucallm_WM1859-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CD223 |
| Reactivity | Human |
| Applications | FC, IF |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | Mouse IgG1/Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IF 1:200-1:1000; FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application |
| Formulation | PBS, pH 7.4 |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Concentration | 0.5mg/ml |
| Clonality | Monoclonal |
| Clone Number | RMMF0114 |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | LAG3 |
| Protein Name | Lymphocyte activation gene 3 protein |
| Other Name | LAG3; / FDC; / Lymphocyte activation gene 3 protein; / LAG-3; / Protein FDC; / CD223 |
| Species | Human |
| Gene ID | 3902 |
| Uniprot | P18627, |
| Species.1 | Mouse |
| Gene ID.1 | 16768 |
| Uniprot.1 | Q61790, |
| Species.2 | Rat |
| Gene ID.2 | 297596 |
| Uniprot.2 | Q5BK54 |
| Cellular Localization | [Lymphocyte activation gene 3 protein]: Cell membrane; Single-pass type I membrane protein .; [Secreted lymphocyte activation gene 3 protein]: Secreted . Produced following cleavage of the main chain. . |
| Tissue Expression | Primarily expressed in activated T-cells and a subset of natural killer (NK) cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Involved in lymphocyte activation. Binds to HLA class-II antigens.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:On cell surface of activated NK and T-lymphocytes., |
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