U-Blot® CD229 (Ly-9) Mouse mAb
Ucallm_WM1860-50
Price range: $268.00 through $328.00
Product details
Background：
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CD229 |
| Reactivity | Human |
| Applications | FC |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | Mouse IgG1/Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application |
| Formulation | PBS, pH 7.4 |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Concentration | 0.5mg/ml |
| Clonality | Monoclonal |
| Clone Number | RMMF0115 |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | LY9 |
| Protein Name | T-lymphocyte surface antigen Ly-9 |
| Other Name | LY9; / CDABP0070; / T-lymphocyte surface antigen Ly-9; / Cell surface molecule Ly-9; / Lymphocyte antigen 9; / CD229 |
| Species | Human |
| Gene ID | 4063 |
| Uniprot | Q9HBG7, |
| Species.1 | Mouse |
| Gene ID.1 | 17085 |
| Uniprot.1 | Q01965 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein. Cell membrane . |
| Tissue Expression | Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients. |
| Signaling_pathway | |
| Research Areas | |
| Function | Alternative products:Experimental confirmation may be lacking for some isoforms,Function:May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains., |
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