Price range: $268.00 through $328.00
Background：
CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. It is expressed on monocytes, granulocytes, NK cells, and basophils. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases.
| Size | 50μL/100μL |
| Target | CD371 |
| Reactivity | Human |
| Applications | FC,IF |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | Mouse IgG2a/Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application |
| Formulation | PBS, pH 7.4 |
| Purification | Protein A |
| Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Concentration | 0.5mg/ml |
| Clonality | Monoclonal |
| Clone Number | RMMF0080 |
| Immunogen | |
| Specificity | Endogenous |
| Gene Name | CLEC12A CLL1 DCAL2 MICL |
| Protein Name | C-type lectin domain family 12 member A (C-type lectin-like molecule 1) (CLL-1) (Dendritic cell-associated lectin 2) (DCAL-2) (Myeloid inhibitory C-type lectin-like receptor) (MICL) (CD antigen CD371) |
| Other Name | CLL1;MICL;CLL-1;DCAL-2;C-type lectin domain family 12 member A;CD371;CD371 nanobody; |
| Species | Human |
| Gene ID | 160364 |
| Uniprot | Q5QGZ9 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane ; Single-pass type II membrane protein . Ligand binding leads to internalization. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
