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Background：
The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011],
| Target | CD43 |
| Reactivity | Human |
| Applications | FC,IF |
| MW(Calculated) | 40kD |
| MW(Observed) | 95kD |
| Host Species | Mouse |
| Isotype | Mouse IgG1/Kappa |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | IHC 1:200-1:1000;WB 1:4000-1:20000;IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application |
| Formulation | PBS, pH 7.4 |
| Source | |
| Purification | Protein A |
| Purity | |
| Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | PTF0061 |
| Immunogen | |
| Sequence | |
| Specificity | Endogenous |
| Gene Name | SPN CD43 |
| Protein Name | Leukosialin (GPL115) (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)] |
| Other Name | Leukosialin (Galactoglycoprotein;GALGP;Leukocyte sialoglycoprotein;Sialophorin;CD antigen CD43) |
| Species | Human |
| Gene ID-1 | 6693 |
| Uniprot | P16150 |
| Species.1 | |
| Gene ID-2 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011], |
| Cellular Localization | Membranous |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | |
| RRID |
