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Background:This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013],
| Target | CDCP1 |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,IP,ELISA |
| MW(Calculated) | 93kD |
| MW(Observed) | 140kD,70kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Modified site | |
| Recommended Dilution Ratio | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Composition | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Source | |
| Purification Process | Protein A |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | PT1548R |
| Immunogen | |
| Sequence | |
| Specificity | Endogenous |
| Gene Name | CDCP1 |
| Protein Name | CUB domain-containing protein 1 |
| Alias | CDCP1;TRASK;CUB domain-containing protein 1;Membrane glycoprotein gp140;Subtractive immunization M plus HEp3-associated 135 kDa protein;SIMA135;Transmembrane and associated with src kinases;CD318 |
| Organism-1 | Human |
| Gene ID-1 | 64866 |
| SwissProt-1 | Q9H5V8 |
| Organism-2 | Mouse |
| GeneID-2 | 109332.0 |
| SwissProt-2 | Q5U462 |
| Organism-3 | |
| GeneID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Cellular Localization | [Isoform 1]: Cell membrane ; Single-pass membrane protein . Shedding may also lead to a soluble peptide.; [Isoform 3]: Secreted. |
