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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/U-Blot® Citrulline-NPM1 (Arg196) Rabbit pAb
SKU: WT9047 Categories: , ,

U-Blot® Citrulline-NPM1 (Arg196) Rabbit pAb

Ucallm_WT9047-100

Price range: $288.00 through $368.00

SKU: WT9047-100
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Product details

Background：
Nucleophosmin(NPM1) isaputativeribosomeassemblyfactorwithahighaffinityforpeptidescontainingnuclear localizationsignals(NLSs). Thetransportofproteinsacrossthenuclearenvelopeisaselective,multistepprocessinvolvingseveralcytoplasmicfactors.Proteinsmustbe recognizedasimportsubstrates,dockat thenuclearporecomplexandtranslocateacrossthenuclearenvelopeinanATP-dependent fashion.Severalcytosolicandnuclearproteinsthatarecentral tothisprocesshavebeenidentified.NPM1isinvolvedinribosomalassembly andrRNAtransport. It ishighlyphosphorylatedbyCdc2kinaseduringmitosis

Specifications

TargetCitrullinated-Nucleophosmin (Arg196)
ReactivityHuman
ApplicationWB
MW(Calculated)33 kDa
MW(Observed)38 kDa
Host SpeciesRabbit
IsotypeIgG
ConjugateUnconjugated
ModificationCitrullination
Modified siteArg196
Recommended dilution ratioWB: 1:1000-1:2000
CompositionPBS, Glycerol, BSA
Source
Purification processProtein A and antigen purified
Purity
StorageStore at -20°C. Avoid repeated freeze-thaw cycles
StabilityStable for 12 months from date of receipt / reconstitution.
Concentration
ClonalityPolyclonal
Clone Number
Immunogenpolypeptide
Sequence
SpecificitySpecific for Nucleophosmin only when citrullinated at Arg196
Gene nameNPM1
Protein NameNucleophosmin
Alternative nameNumatrin, NMP, NMP1
Organism-1Human
Gene ID-14869
SwissProt-1P06748
Organism-2
Gene ID-2
SwissProt-2
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationNucleus,nucleoplasm
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