U-Blot® EGFL7 Rabbit mAb
Product details
Background:This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012],
Specifications
| Size | 50μL/100μL |
| Target | EGFL7 |
| Reactivity | Human, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 30kD |
| MW(Observed) | 30kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1664R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | EGFL7 MEGF7 UNQ187/PRO1449 |
| Protein Name | Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1) |
| Other Name | |
| Species | Human |
| Gene ID | 51162 |
| Uniprot | Q9UHF1, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9QXT5, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q6AZ60 |
| Cellular Localization | Secreted, extracellular space . |
| Tissue Expression | Brain,Kidney,Ovary,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.,similarity:Contains 1 EMI domain.,similarity:Contains 2 EGF-like domains., |
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