Specifications
| Size | 50μL/100μL |
| Target | GOT2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 48kD |
| MW(Observed) | 43kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1780R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | GOT2 |
| Protein Name | Aspartate aminotransferase, mitochondrial |
| Other Name | GOT2; / Aspartate aminotransferase; / mitochondrial; / mAspAT; / Fatty acid-binding protein; / FABP-1; / Glutamate oxaloacetate transaminase 2; / Kynurenine aminotransferase 4; / Kynurenine aminotransferase IV; / Kynurenine--oxoglutarate transaminase 4; / Kynu |
| Species | Human |
| Gene ID | 2806 |
| Uniprot | P00505, |
| Species.1 | Mouse |
| Gene ID.1 | 14719 |
| Uniprot.1 | P05202, |
| Species.2 | Rat |
| Gene ID.2 | 25721 |
| Uniprot.2 | P00507 |
| Cellular Localization | Mitochondrion matrix . Cell membrane . Exposure to alcohol promotes translocation to the cell membrane. . |
| Tissue Expression | Epithelium,Gastric mucosa,Muscle, |
| Signaling_pathway | |
| Research Areas | >>Arginine biosynthesis; / >>Alanine, aspartate and glutamate metabolism; / >>Cysteine and methionine metabolism; / >>Arginine and proline metabolism; / >>Tyrosine metabolism; / >>Phenylalanine metabolism; / >>Phenylalanine, tyrosine and tryptophan biosynthesis; / >>Metabolic pathways; / >>Carbon metabolism; / >>2-Oxocarboxylic acid metabolism; / >>Biosynthesis of amino acids; / >>Fat digestion and absorption |
| Function | Catalytic activity:L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.,cofactor:Pyridoxal phosphate.,Function:Facilitates cellular uptake of long-chain free fatty acids.,miscellaneous:In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.,similarity:Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer., |
