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U-Blot® H_ACVR2B hIgG1 Reference Antibody(Bimbio)
Product details
Background:ACVR2B (Activin A receptor type IIB) is an important cell membrane receptor protein belonging to the TGF-β receptor family, playing a key role in regulating cell growth, proliferation, and differentiation processes. The function of ACVR2B is closely related to its interaction with other signaling proteins such as Activin and Myostatin. By regulating the phosphorylation level of Smad proteins and activating other signaling pathways, ACVR2B can influence the fate and function of cells.
Specifications
| Target | ACVR2B |
| Reactivity | |
| Applications | ELISA;Flow Cytometry |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Human |
| Isotype | IgG1 |
| Conjugate/Modification | Unconjugated |
| Modification | |
| Recommended Dilution Ratio | |
| Formulation Buffer | Phosphate-buffered solution, pH 7.2-7.4. |
| Source | |
| Purification | |
| Purity | > 95% as determined by SDS-PAGE |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -451℃ long term.Avoid repeated freeze-thaw. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | Bimagrumab |
| Immunogen | |
| Sequence | |
| Specificity | |
| Gene Name | |
| Protein Name | |
| Other Name | BYM338,ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB) |
| Species | |
| Gene ID | |
| Uniprot | |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | |
| RRID |
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