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Background:ALPPL2 (alkaline phosphatase, placental-like 2) is a gene that encodes alkaline phosphatase and belongs to the alkaline phosphatase family. The ALPPL2 gene is mainly expressed in the placenta and liver, and plays important physiological functions. Research has shown that ALPPL2 also plays a key role in the development of certain diseases such as osteoporosis, diabetes, and cancer. Therefore, ALPPL2 as an important gene holds significant significance in biomedical research and clinical diagnosis.






