U-Blot® Histone H2AZ Rabbit mAb
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Price range: $700.00 through $1,750.00
Product details
Background:Histone H2AZ is a highly conserved H2A variant independent of DNA replication. It is specifically deposited in gene promoters, enhancers and heterochromatin regions, and regulates chromatin stability and gene transcription. H2AZ participates in key biological processes including cell differentiation, DNA damage repair, stem cell pluripotency maintenance and genome stability regulation. Abnormal expression of H2AZ is closely associated with tumor occurrence and developmental disorders.
Specifications
| Target | Histone H2AZ |
| Reactivity | All Vertebrates |
| Application | WB, ICC. ELISA, Luminex |
| MW(Calculated) | 14kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | Rabbit IgG |
| Conjugate | Unconjugated |
| Modification | Unmodified |
| Modification site | |
| Recommended dilution ratio | WB 0.1 ug/mL – 0.5 ug/mL; ICC 1 μg/mL - 2 μg/mL; ELISA 0.1 ug/mL - 1 ug/mL; Luminex 0.1 ug/mL – 1 ug/mL. |
| Formulation | 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Source | |
| Purification | Protein A affinity purified from an animal origin-free culture supernatant |
| Purity | |
| Storage | -20.0°C |
| Concentration | 1 mg/mL |
| Clonality | Recombinant Monoclonal |
| Clone Number | WR-235 |
| Immunogen | A peptide corresponding to the C-terminus of human Histone H2AZ |
| Sequence | |
| Specificity | This antibody reacts to Histone H2AZ protein, independent of post-translational modifications. No cross reactivity with other histone proteins. |
| Gene name | |
| Protein name | |
| Alternative name | H2AZ, H2A.Z, H2AFZ, H2A/z, H2AZ1 |
| Organism-1 | Human |
| Gene ID‑1 | 3015 |
| SwissProt-1 | P0C0S5 |
| Organism-2 | |
| Gene ID‑2 | |
| SwissProt-2 | |
| Organism-3 | |
| Gene ID‑3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Unnamed: 38 | |
| Unnamed: 39 |
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