U-Blot® Histone H2B (Succinyl Lys120) Rabbit pAb

Price range: $600.00 through $1,500.00

SKU: WT8337-50
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Product details

Background:Histones are subject to a variety of enzyme catalyzed modifications including acetylation, phosphorylation, ubiquitylation etc. Lysine succinylation is a recently identified novel protein post-translational modification (PTM). Lysine succinylation is evolutionarily conserved and abundantly present in proteins in both prokaryotic and eukaryotic cells, suggesting its roles in regulating cellular physiology. This antibody will facilitate studies of lysine succinylation biology by identifying its substrates and studying its function.

Specifications

TargetHistone H2B
ReactivityHuman,Mouse,Rat
ApplicationWB
MW(Calculated)14kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
ConjugateUnconjugated
ModificationSuccinyl
Modification siteLys120
Recommended dilution ratioWB 1:500 - 1:2000
FormulationPBS, Glycerol, BSA
Source
PurificationProtein A and immunogen affinity purified
Purity
StorageStore at -20°C. Avoid freeze/thaw cycles.
Concentration
ClonalityPolyclonal
Clone Number
ImmunogenSuccinylated histone H2B (Lys120) peptide
Sequence
SpecificityThis antibody detects histone H2B only when it is succinylated at Lys120.
Gene name
Protein name
Alternative nameH2BK120su
Organism-1Human
Gene ID‑1255626;3018;3017;8339;8343;8344;8346;8347
SwissProt-1Q96A08;P33778;P62807
Organism-2Mouse
Gene ID‑2319177;319178;319179
SwissProt-2
Organism-3Rat
Gene ID‑324829
SwissProt-3Q00729
Organism-4
Gene ID‑4
SwissProt-4
Cellular Localization
Unnamed: 38
Unnamed: 39
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