U-Blot® Histone H3 (Di Methyl Lys4) Mouse mAb
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Price range: $500.00 through $1,250.00
Product details
Background:Histones undergo various enzyme-catalyzed modifications, including acetylation, methylation, phosphorylation, ubiquitination, etc. H3K4me2 is a methylation modification on histone proteins that are tightly linked to DNA. The researchers found that H3K4me2 gradually accumulated after DNA damage occurred and peaked after 24 hours, then gradually declined. The transient elevation of H3K4me2 after DNA damage suggests that it may be involved in the process of DNA damage repair.
Specifications
| Target | Histone H3 |
| Reactivity | Human,Mouse,Rat |
| Application | WB,IHC-P,ICC/IF,ChIP |
| MW(Calculated) | 15kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | IgG1 |
| Conjugate | Unconjugated |
| Modification | Di Methyl |
| Modification site | Lys4 |
| Recommended dilution ratio | WB 1:500 - 1:1000; IHC-P 1:50 - 1:100; ICC/IF 1:50; ChIP 6 μg per 5x106 cells |
| Formulation | PBS, Glycerol, BSA |
| Source | |
| Purification | Protein G purified |
| Purity | |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Concentration | |
| Clonality | Recombinant Monoclonal |
| Clone Number | WR-207 |
| Immunogen | Dimethylated histone H3 (Lys4) peptide |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein name | |
| Alternative name | H3K4me2 |
| Organism-1 | Human |
| Gene ID‑1 | 8350;8351;8352;8353;8354;8355;8356;8357;8358;8968 |
| SwissProt-1 | P68431;Q71DI3;P84243 |
| Organism-2 | Mouse |
| Gene ID‑2 | 319152;15077;15078 |
| SwissProt-2 | |
| Organism-3 | Rat |
| Gene ID‑3 | 291159;100361558 |
| SwissProt-3 | Q6LED0;P84245 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Unnamed: 38 | |
| Unnamed: 39 |
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