U-Blot® Histone H3 (Succinyl Lys122) Rabbit pAb

Price range: $600.00 through $1,500.00

SKU: WT8336-50
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Product details

Background:Histones are subject to a variety of enzyme catalyzed modifications including acetylation, phosphorylation, ubiquitylation etc. Lysine succinylation is a recently identified novel protein post-translational modification (PTM). Lysine succinylation is evolutionarily conserved and abundantly present in proteins in both prokaryotic and eukaryotic cells, suggesting its roles in regulating cellular physiology. This antibody will facilitate studies of lysine succinylation biology by identifying its substrates and studying its function.

Specifications

TargetHistone H3
ReactivityHuman,Mouse,Rat
ApplicationWB
MW(Calculated)14kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
ConjugateUnconjugated
ModificationSuccinyl
Modification siteLys122
Recommended dilution ratioWB 1:500 - 1:2000
FormulationPBS, Glycerol, BSA
Source
PurificationProtein A and immunogen affinity purified
Purity
StorageStore at -20°C. Avoid freeze/thaw cycles.
Concentration
ClonalityPolyclonal
Clone Number
ImmunogenSuccinylated histone H3 (Lys122) peptide
Sequence
Specificity
Gene name
Protein name
Alternative nameH3K122su
Organism-1Human
Gene ID‑18350;8351;8352;8353;8354;8355;8356;8357;8358;8968
SwissProt-1P68431;Q71DI3;P84243
Organism-2Mouse
Gene ID‑2319152;15077;15078
SwissProt-2
Organism-3Rat
Gene ID‑3291159;100361558
SwissProt-3Q6LED0;P84245
Organism-4
Gene ID‑4
SwissProt-4
Cellular Localization
Unnamed: 38
Unnamed: 39
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