U-Blot® Histone H3 (Succinyl Lys14) Mouse mAb
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Price range: $600.00 through $1,500.00
Product details
Background:Histones are subject to a variety of enzyme catalyzed modifications including acetylation, phosphorylation, ubiquitylation etc. Lysine succinylation is a recently identified novel protein post-translational modification (PTM). Lysine succinylation is evolutionarily conserved and abundantly present in proteins in both prokaryotic and eukaryotic cells, suggesting its roles in regulating cellular physiology. This antibody is specifically designed to facilitate studies of lysine succinylation by enabling the identification of succinylation substrates and providing insights into its functional roles.
Specifications
| Target | Histone H3 |
| Reactivity | Human,Mouse,Rat |
| Application | WB,IHC-P |
| MW(Calculated) | 15kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Succinyl |
| Modification site | Lys14 |
| Recommended dilution ratio | WB 1:500 - 1:2000; IHC-P 1:200 - 1:1000 |
| Formulation | PBS, Glycerol, BSA |
| Source | |
| Purification | Protein G and immunogen affinity purified |
| Purity | |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | |
| Immunogen | Succinylated histone H3 (Lys14) peptide |
| Sequence | |
| Specificity | This antibody detects histone H3 only when it is succinylated at Lys14. |
| Gene name | |
| Protein name | |
| Alternative name | H3K14su |
| Organism-1 | Human |
| Gene ID‑1 | 8350;8351;8352;8353;8354;8355;8356;8357;8358;8968 |
| SwissProt-1 | P68431;Q71DI3;P84243 |
| Organism-2 | Mouse |
| Gene ID‑2 | 319152;15077;15078 |
| SwissProt-2 | |
| Organism-3 | Rat |
| Gene ID‑3 | 291159;100361558 |
| SwissProt-3 | Q6LED0;P84245 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Unnamed: 38 | |
| Unnamed: 39 |
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