U-Blot® Histone H4 (Tri Methyl Lys20) Mouse mAb
Product details
Background:Histone methylation occurs primarily at lysine and arginine residues on the amino-terminal of core histones. Methylation of histones can either increase or decrease transcription of genes, depending on which amino acids (Lys or Arg) in the histones are methylated and how many methyl groups are attached (mono-, di-, tri- methylation on Lys, mono- di-symmetric/asymmetric methylation on Arg). Mostly, lysine methylation occurs primarily on histone H3 Lys4, 9, 27, 36, 79 and H4 Lys20.
Specifications
| Target | Histone H4 |
| Reactivity | Human,Mouse,Rat |
| Application | WB |
| MW(Calculated) | 11kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Tri Methyl |
| Modification site | Lys20 |
| Recommended dilution ratio | WB 1:500 - 1:2000 |
| Formulation | PBS, Glycerol, BSA |
| Source | |
| Purification | Protein G purified |
| Purity | |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Concentration | |
| Clonality | Recombinant Monoclonal |
| Clone Number | WR-218 |
| Immunogen | Trimethylated histone H4 (Lys20) peptide |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein name | |
| Alternative name | H4K20me3 |
| Organism-1 | Human |
| Gene ID‑1 | 121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370 |
| SwissProt-1 | P62805 |
| Organism-2 | Mouse |
| Gene ID‑2 | 100041230 |
| SwissProt-2 | P62806 |
| Organism-3 | Rat |
| Gene ID‑3 | 100360950 |
| SwissProt-3 | P62804 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | |
| Unnamed: 38 | |
| Unnamed: 39 |
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