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Background：Envelope glycoprotein D is a ~43 kDa protein. Envelope glycoprotein that binds to the host cell entry receptors NECTIN1, TNFRSF14/HVEM and 3-O-sulfated heparan sulfate, promoting the virus entry into host cells. May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL.
1. Carfí, A. et al. (2001) Molecular cell 8, 169-79.
PMID: 11511370
