U-Blot® Human Ig light chain λ Mouse mAb
Ucallm_WM1809-50
Price range: $268.00 through $328.00
Product details
Background:This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010],
Specifications
| Size | 50μL/100μL |
| Target | IGLC6 |
| Reactivity | Human |
| Applications | WB, IHC, IF |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | Mouse IgG1/Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:400-1:1000; IHC 1:200-1:1000; IF 1:200-1:1000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMMR1467 |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | IGLC6 |
| Protein Name | Ig lambda-6 chain C region |
| Other Name | Immunoglobulin lambda constant 6 |
| Species | Human |
| Gene ID | |
| Uniprot | P0CF74 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . Cell membrane . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268,聽PubMed:22158414). |
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