Ustekinumab (brand name: Stelara) is a fully human IgG1κ monoclonal antibody developed by Janssen Biotech, a subsidiary of Johnson & Johnson. It is used to treat various immune-mediated diseases, such as psoriasis, psoriatic arthritis, and Crohn's disease. It exerts its immunomodulatory effects by specifically inhibiting the activity of the pro-inflammatory cytokines IL-12 and IL-23.
MW(Calculated)
MW(Observed)
Host Species
Human
Isotype
IgG1,
Conjugate/Modification
Unconjugated
Modification
Recommended Dilution Ratio
Formulation Buffer
phosphate-buffered solution, pH 7.4.
Source
Purification
Purity
> 95% as determined by SDS-PAGE
Storage
Store at 2-8℃ short term (1-2 weeks).Store at ≤ -94℃ long term.Avoid repeated freeze-thaw.