Specifications
| Size | 50μL/100μL |
| Target | IL1RA |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 17kD |
| MW(Observed) | 20kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1741R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | IL1RN IL1F3 IL1RA |
| Protein Name | Interleukin-1 receptor antagonist protein |
| Other Name | IL1RN; / IL1F3; / IL1RA; / Interleukin-1 receptor antagonist protein; / IL-1RN; / IL-1ra; / IRAP; / ICIL-1RA; / IL1 inhibitor; / Anakinra |
| Species | Human |
| Gene ID | 3557 |
| Uniprot | P18510, |
| Species.1 | Mouse |
| Gene ID.1 | 16181 |
| Uniprot.1 | P25085, |
| Species.2 | Rat |
| Gene ID.2 | 60582 |
| Uniprot.2 | P25086 |
| Cellular Localization | [Isoform 1]: Secreted.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm. |
| Tissue Expression | The intracellular form of IL1RN is predominantly expressed in epithelial cells. |
| Signaling_pathway | Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction |
| Research Areas | >>Cytokine-cytokine receptor interaction |
| Function | defense response, inflammatory response, immune response, response to wounding, response to endogenous stimulus, response to hormone stimulus, response to organic substance, response to corticosteroid stimulus,response to steroid hormone stimulus, response to glucocorticoid stimulus, |
