U-Blot® KHK Rabbit mAb
Ucallm_WR5759-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | KHK |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 33kD |
| MW(Observed) | 33kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1721R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | KHK |
| Protein Name | KHK |
| Other Name | |
| Species | Human |
| Gene ID | 3795 |
| Uniprot | P50053, |
| Species.1 | Mouse |
| Gene ID.1 | 16548 |
| Uniprot.1 | P97328, |
| Species.2 | Rat |
| Gene ID.2 | 25659 |
| Uniprot.2 | Q02974 |
| Cellular Localization | cytoplasm,cytosol,extracellular exosome, |
| Tissue Expression | Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye. |
| Signaling_pathway | |
| Research Areas | >>Fructose and mannose metabolism; / >>Metabolic pathways |
| Function | Catalytic activity:ATP + D-fructose = ADP + D-fructose 1-phosphate.,Caution:Form C has not yet been fully sequenced in its N-terminal (from 1-69).,Disease:Defects in KHK are the cause of fructosuria [MIM:229800]. Fructosuria is a benign defect of intermediary metabolism.,enzyme regulation:Requires potassium. Inhibition by ADP.,pathway:Carbohydrate metabolism; fructose metabolism.,similarity:Belongs to the carbohydrate kinase pfkB family.,subunit:Dimer of A-A, A-C or C-C.,tissue specificity:Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye., |
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