Product details
Background：
U-Blot® KINH Rabbit mAb
Ucallm_WR6066-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | KINH |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 110kD |
| MW(Observed) | 110kD |
| Host Species | Rabbit |
| Isotype | IgG, Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year (Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1964R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | KIF5B KNS KNS1 |
| Protein Name | KINH |
| Other Name | Kinesin-1 heavy chain; / Conventional kinesin heavy chain; / Ubiquitous kinesin heavy chain; / UKHC |
| Species | Human |
| Gene ID | 3799 |
| Uniprot | P33176, |
| Species.1 | Mouse |
| Gene ID.1 | 16573 |
| Uniprot.1 | Q61768, |
| Species.2 | Rat |
| Gene ID.2 | 117550 |
| Uniprot.2 | Q2PQA9 |
| Cellular Localization | Cytoplasm , cytoskeleton . Cytolytic granule membrane . Lysosome membrane; Peripheral membrane protein; Cytoplasmic side . Uniformly distributed between soma and neurites in hippocampal neurons. . |
| Tissue Expression | Muscle ,Placenta ,Uterus , |
| Signaling_pathway | Organismal Systems >> Nervous system >> Dopaminergic synapse;Human Diseases >> Cancer: specific types >> Non-small cell lung cancer;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases |
| Research Areas | >>Endocytosis; / >>Dopaminergic synapse; / >>Alzheimer disease; / >>Parkinson disease; / >>Amyotrophic lateral sclerosis; / >>Huntington disease; / >>Prion disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Salmonella infection; / >>Non-small cell lung cancer |
| Function | Domain:Composed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule) , a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains) , vesicles and membranous organelles. ,Function:Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. ,similarity:Belongs to the kinesin-like protein family. ,similarity:Belongs to the kinesin-like protein family. Kinesin subfamily. ,similarity:Contains 1 kinesin-motor domain. ,subcellular location:Uniformly distributed between soma and neurites in hippocampal neurons. ,subunit:Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 (By similarity) . Interacts with SYBU. Interacts with JAKMIP1. , |
Please login to post questions
Related products
