Specifications
| Size | 50μL/100μL |
| Target | LONP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 106kD |
| MW(Observed) | 106kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1755R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | LONP1 PRSS15 |
| Protein Name | LONM |
| Other Name | Lon protease homolog, mitochondrial; / LONHs; / Lon protease-like protein; / LONP; / Mitochondrial ATP-dependent protease Lon; / Serine protease 15 |
| Species | Human |
| Gene ID | 9361 |
| Uniprot | P36776, |
| Species.1 | Mouse |
| Gene ID.1 | 74142 |
| Uniprot.1 | Q8CGK3, |
| Species.2 | Rat |
| Gene ID.2 | 170916 |
| Uniprot.2 | Q924S5 |
| Cellular Localization | Mitochondrion matrix . |
| Tissue Expression | Duodenum, heart, lung and liver, but not thymus. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Required for intramitochondrial proteolysis. Catalyzes the initial steps of protein degradation. Hydrolyzes ATP and degrades protein and peptide substrates in an ATP-dependent manner. Binds to single-stranded but not to double-stranded DNA.,similarity:Belongs to the peptidase S16 family.,similarity:Contains 1 Lon domain.,tissue specificity:Duodenum, heart, lung and liver, but not thymus., |
