Specifications
| Size | 50μL/100μL |
| Target | MKP-2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, IP, ELISA |
| MW(Calculated) | 43kD |
| MW(Observed) | 40kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1722R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | DUSP4 |
| Protein Name | Dual specificity protein phosphatase 4 |
| Other Name | DUSP4; / MKP2; / VH2; / Dual specificity protein phosphatase 4; / Dual specificity protein phosphatase hVH2; / Mitogen-activated protein kinase phosphatase 2; / MAP kinase phosphatase 2; / MKP-2 |
| Species | Human |
| Gene ID | 1846 |
| Uniprot | Q13115, |
| Species.1 | Mouse |
| Gene ID.1 | 319520 |
| Uniprot.1 | Q8BFV3, |
| Species.2 | Rat |
| Gene ID.2 | 60587 |
| Uniprot.2 | Q62767 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Skin,Uterus, |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> MAPK signaling pathway |
| Research Areas | >>MAPK signaling pathway |
| Function | Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,Catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,Function:Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain., |
