U-Blot® O-Linked N-Acetylglucosamine Rabbit mAb
Ucallm_WR5895-50
Price range: $288.00 through $368.00
Product details
Background：
O-Linked N-Acetylglucosamine (O-GlcNAc) is a post-translational modification involving the addition of a single N-acetylglucosamine moiety to the serine or threonine residues of nuclear and cytoplasmic proteins. This dynamic modification is sometimes referred to as O-GlcNAcylation. The molecular mass of the O-GlcNAc group itself is approximately 203 Da. This modification is expressed widely across various tissues notably in the brain and pancreas. O-GlcNAc plays a critical role in regulating protein function stability and interaction.
Specifications
| Size | 50μL/100μL |
| Target | O-Linked N-Acetylglucosamine |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | All |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Pan-PTM |
| Recommended Dilution Ratio | WB 1:200-1:1000; IF 1:200-1:1000; ELISA 1:5000-1:20000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1697R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | |
| Protein Name | |
| Other Name | |
| Species | |
| Gene ID | |
| Uniprot | |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | O-Linked N-Acetylglucosamine (O-GlcNAc) is a post-translational modification involving the addition of a single N-acetylglucosamine moiety to the serine or threonine residues of nuclear and cytoplasmic proteins. |
| Tissue Expression | This modification is expressed widely across various tissues notably in the brain and pancreas. |
| Signaling_pathway | |
| Research Areas | Nutrient sensing and insulin signaling; / Cellular signaling and metabolism; / Diabetes (insulin resistance, type 2 diabetes); / Cancer research (tumorigenesis, migration, invasion, ferroptosis); / Transcription, stress response |
| Function | O-GlcNAc plays a critical role in regulating protein function stability and interaction. |
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