U-Blot® Pan-Phospho-Serine Rabbit pAb
Ucallm_WT9181-100
Price range: $450.00 through $1,150.00
Product details
Background:Serine phosphorylation is one of the most prevalent and reversible post-translational modifications in eukaryotic proteins. Catalyzed by kinases and reversed by phosphatases, this modification covalently attaches a phosphate group to the hydroxyl group of serine residues. It alters protein charge, conformation and intermolecular interactions, acting as a core molecular switch to regulate cell cycle, signal transduction, proliferation, differentiation, metabolism and immune response. Dysregulated serine phosphorylation is implicated in inflammation, cancer and multiple human diseases.
Specifications
| Target | Phospho-Serine |
| Reactivity | Species Independent |
| Application | ELISA,WB,IHC,IP |
| MW(Calculated) | Multiple |
| MW(Observed) | Multiple |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Serine phosphorylation |
| Modification Site | |
| Recommended dilution ratio | ELISA 1:250; WB 1:250; IP 10 µg/mg crude protein; IHC 1:50 |
| Composition | 250ug/mL antibody stored in PBS, 50% glycerol |
| Purification process | Affinity purified with serine-phosphorylated peptide immobilized on agarose |
| Storage | Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Polyclonal |
| Clone Number | |
| Immunogen | Affinity purified with serine-phosphorylated peptide immobilized on agarose |
| Gene Name | |
| Protein Name | |
| Alternative name | |
| Organism-1 | |
| Gene ID | |
| SwissProt-1 | |
| Cellular Localization |
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