U-Blot® Pan-Phospho-Tyrosine Rabbit mAb-BSA and Azide free
Ucallm_WT9124R-100
Price range: $550.00 through $1,400.00
Product details
Background:Phospho-Tyrosine (pY) is a widely occurring post-translational modification on tyrosine residues in eukaryotic cells. This modification is catalyzed by protein tyrosine kinases (PTKs), which covalently attach a phosphate group to the phenolic hydroxyl group of tyrosine, and can be reversibly removed by protein tyrosine phosphatases (PTPs). Tyrosine phosphorylation serves as a core mechanism in cellular signal transduction, regulating cell proliferation, differentiation, apoptosis, migration, and metabolism. Dysregulation of tyrosine phosphorylation is closely associated with tumorigenesis, immune disorders, neurodegenerative diseases, and other pathological conditions, making it a critical target in cell signaling and therapeutic drug development.
Specifications
| Target | Phospho-Tyrosine |
| Reactivity | Human, Mouse，Rat |
| Application | WB |
| MW(Calculated) | Multiple |
| MW(Observed) | Multiple |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Tyrosine Phosphorylation |
| Modification Site | Tyr（Y） |
| Recommended dilution ratio | WB 1:1000 |
| Composition | PBS |
| Purification process | Protein A |
| Storage | Upon delivery centrifugate. Reconstitute with 100 μL distilled water (1.0 mg/mL after restoration). Aliquot and store at -80 °C. Avoid freeze / thaw cycles. |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Recombinant monoclonal |
| Clone Number | W-R16 |
| Immunogen | polypeptide |
| Gene Name | |
| Protein Name | |
| Alternative name | P-Tyr |
| Organism-1 | |
| Gene ID | |
| SwissProt-1 | |
| Cellular Localization |
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