U-Blot® Pan-SUMO1/2/3 Mouse mAb

Price range: $450.00 through $1,150.00

SKU: WT9110-100
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Product details

Background:Small Ubiquitin-like Modifier (SUMO) is a family of ubiquitin-like proteins that covalently conjugate to lysine residues of target substrates, regulating diverse cellular processes including protein stability, transcriptional regulation, DNA repair, cell cycle progression and immune response. SUMO1, SUMO2 and SUMO3 are the major mammalian SUMO isoforms with overlapping yet distinct biological functions. Pan-SUMO antibody enables broad detection of global SUMOylation events, recognizing protein substrates modified by SUMO1, SUMO2 and SUMO3.

Specifications

TargetSUMO1 / SUMO2 / SUMO3
ReactivityHuman, Mouse,Rat
ApplicationWB,IHC-P
MW(Calculated)Multiple
MW(Observed)Multiple
Host SpeciesMouse
IsotypeIgG
ConjugateUnconjugated
ModificationSUMOylation
Modification SiteLys(K)
Recommended dilution ratioWB 1:500-2000;IHC-P 1:200-1:1000
CompositionPBS, Glycerol, BSA
Purification processAntibodies are purified by protein G-conjugated agarose followed by peptide affinity chromatography
StorageStore at -20°C. Avoid repeated freeze-thaw cycles
StabilityStable for 12 months from date of receipt / reconstitution.
Concentration
ClonalMonoclonal
Clone Number
Immunogenpolypeptide
Gene NameSUMO1, SUMO2, SUMO3
Protein NameSmall ubiquitin-related modifier 1/2/3
Alternative name
Organism-1Human
Gene ID7341 (SUMO1), 6612 (SUMO2), 6613 (SUMO3)
SwissProt-1P63165, P61956, P55854
Cellular LocalizationNucleus, Cytoplasm
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