Price range: $288.00 through $368.00
Background:Tumor protein P53, also known as p53, cellular tumor antigen p53, is an isoform of a protein encoded by homologous genes in various organisms. p53 is crucial in multicellular vertebrates, where it prevents cancer formation.As such, p53 has been described as “the guardian of the genome” because of its role in conserving stability by preventing genome mutation. Hence TP53 is classified as a tumor suppressor gene.
| Target | Phospho-p53 (Ser15) |
| Reactivity | Human |
| Application | WB,ICC/IF |
| MW(Calculated) | 44 kDa |
| MW(Observed) | 53 kDa |
| Host Species | Mouse |
| Isotype | IgG1/Kappa |
| Conjugate | Unconjugated |
| Modification | Phosphorylation |
| Modification Site | Ser15 |
| Recommended dilution ratio | WB 1:500-1:1000; ICC/IF 1:50 |
| Composition | PBS, Glycerol, BSA |
| Purification process | Protein A affinity purification |
| Storage | Store at -20°C. Avoid repeated freeze-thaw cycles |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Recombinant monoclonal |
| Clone Number | W-R58 |
| Immunogen | polypeptide |
| Gene Name | TP53 |
| Protein Name | Tumor protein p53 |
| Alternative name | TP53, cellular tumor antigen p53 |
| Organism-1 | Human |
| Gene ID | 7157 |
| SwissProt-1 | P04637 |
| Cellular Localization | Nucleus, Cytoplasm |
