U-Blot® Phospho-(Ser/Thr) PDK1 Docking Motif Mouse mAb
Product details
Background:Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine in a hydrophobic motif. For example, Akt, a kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site preceded by Phe at -4 and -1 and followed by Tyr at +1. RSK2, p70 S6 kinase and certain PKC isoforms also contain a similar consensus phosphorylation motif. Phosphorylation of these motifs is required for binding to 3-phosphoinositide dependent kinase 1 (PDK1). Phospho-(Ser/Thr) PDK1 Docking Motif Mouse mAb is a powerful tool for the characterization of phosphorylated PDK1 docking motifs and the identification of new proteins with PDK1 docking motifs.
Specifications
| Target | Phospho-(Ser/Thr) PDK1 Docking Motif |
| Reactivity | Human |
| Application | WB |
| MW(Calculated) | All kDa |
| MW(Observed) | / |
| Host Species | Mouse |
| Isotype | IgG2a/Kappa |
| Conjugate | Unconjugated |
| Modification | Phosphorylation |
| Modification Site | Serine/Threonine residues in the PDK1 docking motif |
| Recommended dilution ratio | WB 1:500-1:1000 |
| Composition | PBS, Glycerol, BSA |
| Purification process | Protein A affinity purification |
| Storage | Store at -20°C. Avoid repeated freeze-thaw cycles |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Recombinant monoclonal |
| Clone Number | W-R31 |
| Immunogen | polypeptide |
| Gene Name | |
| Protein Name | |
| Alternative name | |
| Organism-1 | Human |
| Gene ID | |
| SwissProt-1 | |
| Cellular Localization |
Please login to post questions





