U-Blot® Phospho-(Ser/Thr) PDK1 Docking Motif Mouse mAb

Price range: $288.00 through $368.00

SKU: WT9056-100
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Product details

Background:Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine in a hydrophobic motif. For example, Akt, a kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site preceded by Phe at -4 and -1 and followed by Tyr at +1. RSK2, p70 S6 kinase and certain PKC isoforms also contain a similar consensus phosphorylation motif. Phosphorylation of these motifs is required for binding to 3-phosphoinositide dependent kinase 1 (PDK1). Phospho-(Ser/Thr) PDK1 Docking Motif Mouse mAb is a powerful tool for the characterization of phosphorylated PDK1 docking motifs and the identification of new proteins with PDK1 docking motifs.

Specifications

TargetPhospho-(Ser/Thr) PDK1 Docking Motif
ReactivityHuman
ApplicationWB
MW(Calculated)All kDa
MW(Observed)/
Host SpeciesMouse
IsotypeIgG2a/Kappa
ConjugateUnconjugated
ModificationPhosphorylation
Modification SiteSerine/Threonine residues in the PDK1 docking motif
Recommended dilution ratioWB 1:500-1:1000
CompositionPBS, Glycerol, BSA
Purification processProtein A affinity purification
StorageStore at -20°C. Avoid repeated freeze-thaw cycles
StabilityStable for 12 months from date of receipt / reconstitution.
Concentration
ClonalRecombinant monoclonal
Clone NumberW-R31
Immunogenpolypeptide
Gene Name
Protein Name
Alternative name
Organism-1Human
Gene ID
SwissProt-1
Cellular Localization
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