U-Blot® Phospho-Tyrosine MultiPTM Rabbit Monoclonal Antibody mix
Product details
Background:Phospho-Tyrosine (pY) is a widely occurring post-translational modification on tyrosine residues in eukaryotic cells. This modification is catalyzed by protein tyrosine kinases (PTKs), which covalently attach a phosphate group to the phenolic hydroxyl group of tyrosine, and can be reversibly removed by protein tyrosine phosphatases (PTPs). Tyrosine phosphorylation serves as a core mechanism in cellular signal transduction, regulating cell proliferation, differentiation, apoptosis, migration, and metabolism. Dysregulation of tyrosine phosphorylation is closely associated with tumorigenesis, immune disorders, neurodegenerative diseases, and other pathological conditions, making it a critical target in cell signaling and therapeutic drug development.
Specifications
| Target | Phospho-Tyrosine |
| Reactivity | Species Independent |
| Application | WB,IHC-P,ICC/IF,FC |
| MW(Calculated) | Multiple |
| MW(Observed) | Multiple |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Tyrosine Phosphorylation |
| Modification Site | Tyr(Y) |
| Recommended dilution ratio | WB 1:1000;IHC-P 1:100-1:200;ICC/IF 1:100-1:200;FC 1:100-1:200 |
| Composition | PBS, Glycerol, BSA,NaN3 |
| Purification process | |
| Storage | Store at -20°C. Avoid repeated freeze-thaw cycles |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Monoclonal |
| Clone Number | |
| Immunogen | polypeptide |
| Gene Name | |
| Protein Name | |
| Alternative name | P-Tyr |
| Organism-1 | |
| Gene ID | |
| SwissProt-1 | |
| Cellular Localization |





