$168.00
Background：
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
| Target | Prolactin |
| Reactivity | Human |
| Applications | IHC |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | IgG1,Kappa |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | Ready to use for IHC / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004) |
| Formulation | The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300 |
| Source | |
| Purification | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Purity | |
| Storage | 2°C to 8°C/1 year,Ship by ice bag |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | ABT220 |
| Immunogen | Synthesized peptide derived from human Prolactin AA range: 100-227 |
| Sequence | |
| Specificity | The antibody can specifically recognize human Prolactin protein. |
| Gene Name | PRL |
| Protein Name | Prolactin |
| Other Name | Prolactin; / PRL |
| Species | Human |
| Gene ID-1 | 5617 |
| Uniprot | P01236 |
| Species.1 | |
| Gene ID-2 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011], |
| Cellular Localization | Cytoplasmic |
| Tissue Expression | Cytoplasmic |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Prolactin signaling pathway;Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction |
| Research Areas | >>Cytokine-cytokine receptor interaction; / >>Neuroactive ligand-receptor interaction; / >>PI3K-Akt signaling pathway; / >>JAK-STAT signaling pathway; / >>Prolactin signaling pathway |
| Function | Function:Prolactin acts primarily on the mammary gland by promoting lactation.,online information:Prolactin entry,similarity:Belongs to the somatotropin/prolactin family., |
| RRID |
