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Home/Reagents/Antibody/Biosimilar & Bispecific Antibodies/U-Blot® Research Grade Cadonilimab
SKU: WA2566 Categories: ,

U-Blot® Research Grade Cadonilimab

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$9,999.00

SKU: WA2566-50
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Product details

Background：Danvilostomig is an anti-CTLA4/PDCD1 monoclonal antibody.
• Cancer immunotherapy using checkpoint blockade., PMID:29567705
• The blockade of immune checkpoints in cancer immunotherapy., PMID:22437870
• Immune-related adverse events of checkpoint inhibitors., PMID:32382051
• Immune Checkpoint Blockade in Cancer Therapy., PMID:25605845
• Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy., PMID:29256113
• Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination., PMID:27141885
• Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints., PMID:30184160
• Tumour- and class-specific patterns of immune-related adverse events of immune checkpoint inhibitors: a systematic review., PMID:28945858
• Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer., PMID:34088360
• Fundamental Mechanisms of Immune Checkpoint Blockade Therapy., PMID:30115704

Specifications

TargetCD1
ReactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host SpeciesHumanized
IsotypeIgG1-kappa-[scFv-heavy-lambda]2
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition0.01M PBS, pH 7.4.
Purification ProcessProtein A/G purified from cell culture supernatant.
Purity>95% purity as determined by SDS-PAGE.
Storage ConditionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Concentration
ClonalityMonoclonal
Clone Number
ImmunogenMammalian Cells
Gene Name
Protein Name
AliasProgrammed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279, CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4
Species
Gene ID-1Q15116 & P16410
Uniprot
Species.1
Gene ID
Uniprot.1
Species.2
Gene ID.1
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
DescriptionBackground：Danvilostomig is an anti-CTLA4/PDCD1 monoclonal antibody.<br>• Cancer immunotherapy using checkpoint blockade., PMID:29567705<br />• The blockade of immune checkpoints in cancer immunotherapy., PMID:22437870<br />• Immune-related adverse events of checkpoint inhibitors., PMID:32382051<br />• Immune Checkpoint Blockade in Cancer Therapy., PMID:25605845<br />• Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy., PMID:29256113<br />• Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination., PMID:27141885<br />• Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints., PMID:30184160<br />• Tumour- and class-specific patterns of immune-related adverse events of immune checkpoint inhibitors: a systematic review., PMID:28945858<br />• Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer., PMID:34088360<br />• Fundamental Mechanisms of Immune Checkpoint Blockade Therapy., PMID:30115704<br />
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
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