U-Blot® Research Grade Samrotamab

$9,999.00

SKU: WA3504-50
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Product details

Background:Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15.
• A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid., PMID:11785964
• Mediators of inflammation and regeneration., PMID:21677081
• Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix., PMID:16098915
• High lib mRNA expression in breast carcinomas., PMID:15368894

Specifications

TargetLeucine-rich repeat protein induced by beta-amyloid homolog
ReactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host SpeciesHumanized
IsotypeIgG1-kappa
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition0.01M PBS, pH 7.4.
Purification ProcessProtein A/G purified from cell culture supernatant.
Purity>95% purity as determined by SDS-PAGE.
Storage ConditionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Concentration
ClonalityMonoclonal
Clone Number
ImmunogenMammalian Cells
Gene Name
Protein Name
AliasLeucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib
Species
Gene ID-1Q8TF66
Uniprot
Species.1
Gene ID
Uniprot.1
Species.2
Gene ID.1
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
DescriptionBackground:Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15.<br>• A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid., PMID:11785964<br />• Mediators of inflammation and regeneration., PMID:21677081<br />• Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix., PMID:16098915<br />• High lib mRNA expression in breast carcinomas., PMID:15368894<br />
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
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