U-Blot® Research Grade Tamrintamab
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$9,999.00
Product details
Background：Technetium (99mTc) pintumomab (INN) is a mouse monoclonal antibody for the imaging of adenocarcinoma. It is labelled with the radioisotope technetium-99m.
• ADC: a deadly killer of platinum resistant ovarian cancer., PMID:39367438
• A mini-overview of antibody-drug conjugates in platinum-resistant ovarian cancer: A preclinical and clinical perspective., PMID:39922351
• Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis., PMID:21724266
• Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity., PMID:32325220
• Tamrintamab pamozirine (SC-003) in patients with platinum-resistant/refractory ovarian cancer: Findings of a phase 1 study., PMID:32513564
• The testis-specifically expressed Dpep3 is not essential for male fertility in mice., PMID:31212048
• Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies., PMID:30097533
• Effects of varicocele and microsurgical varicocelectomy on the metabolites in semen., PMID:35338186
• Identification of two additional members of the membrane-bound dipeptidase family., PMID:12738806
Specifications
| Target | DPEP3 |
| Reactivity | Human |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Humanized |
| Isotype | IgG1-kappa |
| Conjugate/Modification | |
| Modification | |
| Recommended Dilution Ratio | |
| Composition | 0.01M PBS, pH 7.4. |
| Purification Process | Protein A/G purified from cell culture supernatant. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Storage Condition | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | |
| Immunogen | Mammalian Cells |
| Gene Name | |
| Protein Name | |
| Alias | DPEP3, Dipeptidase 3 |
| Species | |
| Gene ID-1 | Q9H4B8 |
| Uniprot | |
| Species.1 | |
| Gene ID | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.1 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Description | Background：Technetium (99mTc) pintumomab (INN) is a mouse monoclonal antibody for the imaging of adenocarcinoma. It is labelled with the radioisotope technetium-99m.<br>• ADC: a deadly killer of platinum resistant ovarian cancer., PMID:39367438<br />• A mini-overview of antibody-drug conjugates in platinum-resistant ovarian cancer: A preclinical and clinical perspective., PMID:39922351<br />• Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis., PMID:21724266<br />• Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity., PMID:32325220<br />• Tamrintamab pamozirine (SC-003) in patients with platinum-resistant/refractory ovarian cancer: Findings of a phase 1 study., PMID:32513564<br />• The testis-specifically expressed Dpep3 is not essential for male fertility in mice., PMID:31212048<br />• Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies., PMID:30097533<br />• Effects of varicocele and microsurgical varicocelectomy on the metabolites in semen., PMID:35338186<br />• Identification of two additional members of the membrane-bound dipeptidase family., PMID:12738806<br /> |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
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