U-Blot® Research Grade Urtoxazumab
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$9,999.00
Product details
Background：Urtoxazumab (TMA-15) is a humanizedized monoclonal antibody against Shiga toxin (Stx) 2.
• Shiga Toxin (Stx) Classification, Structure, and Function., PMID:25530917
• Shiga-toxin-converting bacteriophages., PMID:11686382
• Escherichia albertii Pathogenesis., PMID:32588811
• Shiga Toxin-Producing Escherichia coli Infections during Pregnancy., PMID:30360505
• Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing Escherichia coli (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice., PMID:33467588
• Targeting bacterial toxins., PMID:22441768
• Shiga toxin-induced haemolytic uraemic syndrome and the role of antibiotics: a global overview., PMID:31150744
• L-Arabinose inhibits Shiga toxin type 2-converting bacteriophage induction in Escherichia coli O157:H7., PMID:37332116
• Shiga toxin 2a and Enteroaggregative Escherichia coli–a deadly combination., PMID:26039753
• Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model., PMID:36977098
Specifications
| Target | shiga toxin type 2stx2B |
| Reactivity | Escherichia coli |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Humanized |
| Isotype | IgG1-kappa |
| Conjugate/Modification | |
| Modification | |
| Recommended Dilution Ratio | |
| Composition | 0.01M PBS, pH 7.4. |
| Purification Process | Protein A/G purified from cell culture supernatant. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Storage Condition | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | |
| Immunogen | Mammalian Cells |
| Gene Name | |
| Protein Name | |
| Alias | shiga toxin type 2stx2B |
| Species | |
| Gene ID-1 | Q07871 |
| Uniprot | |
| Species.1 | |
| Gene ID | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.1 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Description | Background：Urtoxazumab (TMA-15) is a humanizedized monoclonal antibody against Shiga toxin (Stx) 2.<br>• Shiga Toxin (Stx) Classification, Structure, and Function., PMID:25530917<br />• Shiga-toxin-converting bacteriophages., PMID:11686382<br />• <i>Escherichia albertii</i> Pathogenesis., PMID:32588811<br />• Shiga Toxin-Producing <i>Escherichia coli</i> Infections during Pregnancy., PMID:30360505<br />• Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing <i>Escherichia coli</i> (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice., PMID:33467588<br />• Targeting bacterial toxins., PMID:22441768<br />• Shiga toxin-induced haemolytic uraemic syndrome and the role of antibiotics: a global overview., PMID:31150744<br />• L-Arabinose inhibits Shiga toxin type 2-converting bacteriophage induction in <i>Escherichia coli</i> O157:H7., PMID:37332116<br />• Shiga toxin 2a and Enteroaggregative Escherichia coli--a deadly combination., PMID:26039753<br />• Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model., PMID:36977098<br /> |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
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