U-Blot® S100A6 Mouse mAb (Ready to Use)
Ucallm_WM1658R
$168.00
Product details
Background：
S100 calcium binding protein A6(S100A6) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008],
Specifications
| Size | 6mL |
| Target | S100A6 |
| Reactivity | Human |
| Applications | IHC |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | IgG1,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | Ready to use for IHC / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300 |
| Purification | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Storage | 2°C to 8°C/1 year,Ship by ice bag |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMM-S100A6 |
| Immunogen | Synthesized peptide derived from human S100A6 AA range: 50-90 |
| Specificity | The antibody can specifically recognize human S100A6 protein. |
| Gene Name | S100A6 CACY |
| Protein Name | S100A6 |
| Other Name | Protein S100-A6; / Calcyclin; / Growth factor-inducible protein 2A9; / MLN 4; / Prolactin receptor-associated protein; / PRA; / S100 calcium-binding protein A6 |
| Species | Human |
| Gene ID | 6277 |
| Uniprot | P06703 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nuclear, Cytoplasmic |
| Tissue Expression | Brain,Fibroblast,Placenta,Platelet, |
| Signaling_pathway | |
| Research Areas | |
| Function | induction:Preferentially expressed when quiescent fibroblasts are stimulated to proliferate. It is inducible by growth factors and overexpressed in acute myeloid leukemias.,miscellaneous:This protein co-purified with the prolactin receptor.,PTM:The N-terminus is blocked.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer, antiparallel. Interacts with SUGT1., |
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