SKU: WM1753R Categories: ,

U-Blot® S100P Mouse mAb (Ready to Use)

$168.00

SKU: WM1753R
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Product details

Background:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008],

Specifications

TargetS100P
ReactivityHuman
ApplicationsIHC
MW(Calculated)
MW(Observed)
Host SpeciesMouse
IsotypeIgG1,Kappa
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioReady to use for IHC / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
FormulationThe prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
Source
PurificationThe antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Purity
Storage2°C to 8°C/1 year,Ship by ice bag
Concentration
ClonalityMonoclonal
Clone NumberABT375
ImmunogenSynthesized peptide derived from human S100P AA range: 1-95
Sequence
SpecificityThe antibody can specifically recognize human S100P protein.
Gene NameS100P S100E
Protein NameMIG9; Migration inducing gene 9; Protein S100-E; Protein S100-P; Protein S100P; S100 calcium binding protein P; S100 calcium-binding protein P; S100 P; S100E; S100P; S100P_HUMAN
Other NameMIG9; / Migration inducing gene 9; / Protein S100-E; / Protein S100-P; / Protein S100P; / S100 calcium binding protein P; / S100 calcium-binding protein P; / S100 P; / S100E; / S100P; / S100P_HUMAN
SpeciesHuman
Gene ID-16286
UniprotP25815
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
BackgroundThe protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008],
Cellular LocalizationNuclear, Cytoplasmic
Tissue ExpressionPlacenta/ Appendix
Signaling_pathway
Research Areas
Functionmiscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.,
RRID
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