U-Blot® SOX11 Rabbit mAb
Ucallm_WR5275-50
Price range: $268.00 through $328.00
Product details
Background:This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | SOX11 |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 47kD |
| MW(Observed) | 65kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:1000-1:20000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1520R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | SOX11 |
| Protein Name | Transcription factor SOX-11 |
| Other Name | |
| Species | Human |
| Gene ID | 6664 |
| Uniprot | P35716, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q7M6Y2, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P0C1G9 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probably important in the developing nervous system. May also have a role in tissue modeling during development.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Expressed mainly in the nervous system., |
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